2022 NFL Week 2 Odds

Full stadiums, outrageous plays, upsets, games coming down to the wire, and hyped-up rookies making big plays.

The NFL Week 1 was a great way to start the season and let’s hope for more of the same in Week 2.

With NFL odds for Week 2 available let’s preview all 15 games for this coming weekend.

New England Patriots (-280) @ New York Jets (+225)

Patriots: The New England Patriots are coming off a 1 point loss against the Miami Dolphins. However, Rookie QB Mac Jones on his first start in the NFL threw for 281 yds for 1 TD and completed 29/39 of his passes. He looked like a seasoned starter and is definitely showing encouraging signs.

However, the offense needs to improve in the red zone, having only scored 1 TD on 5 trips to the Dolphins red zone. The offense should find it easier in the red zone this week against the Jets’ secondary which was solid last week but isn’t as good as the Dolphins.

The Pats defense is also looking solid after limiting the Dolphins to only 202 yds passing, 74 yds rushing with 2 TD and 1 INT.

They should continue to improve with new additions Matt Judon, Davon Godchaux, and Jalen Mills still learning the ropes, but the Pats will still be without star CB Stephon Gilmore who remains on IR.

Jets: The Jets came out the gate slowly against the Panthers in week 1, under their new head coach Robert Saleh. They didn’t score a single point in the first half of the game, finding themselves 0-16 down at halftime.

However, they had a much better second half and almost pulled off an upset, eventually falling short 14-19. Rookie QB Zach Wilson had a decent first game in the NFL throwing for 258 yds for 2TD, 1 INT, and completing 20/37 passes.

But Wilson was sacked 6 times, which was down to a combination of him holding onto the ball for too long and their very young and inexperienced offensive line struggling to cope with the Panthers’ sustained pressure. The Jets were without star tackle Mekhi Becton who will also miss the game against the Pats.

The intensity on Wilson won’t let up in week 2 with the Pats boasting a quality pass-rushing group including Judon and Josh Uche. If the Jets are to win this game their Defence must put in another solid performance and the O-line will have to step up dramatically.

The Pats should be feeling confident about their chances in Week 2, heading in as heavy favorites against the Jets.

I am taking the Pats but there is not much value at the odds, but I shall add them to my parlay.

Denver Broncos (-275) @ Jacksonville Jaguars (+220)

Broncos: The Denver Broncos had a big Week 1 win against the Giants. Vic Fangio’s decision to start Teddy Bridgewater ahead of Drew Lock paid off with Bridgewater (264 yds, 2 TDs, 0 INT).

He showed us what he is capable of, with great ball distribution and not giving up an interception. The question is whether he can sustain this level of QB play. The Denver defense is looking strong this year having only allowed Daniel Jones a 59.5 completion percentage last week.

Denver will have a race against time to bring Bradley Chubb back to partner Von Miller at OLB, who had 2 sacks against the Giants. The Broncos were a powerhouse in the running game, enjoying 165 yds rushing, with over 100 yds for Melvin Gordon alone.

Denver should have a lot more joy in Week 2 rushing against an average Jags defense. However, they will be missing star WR Jerry Jeudy who was injured in Week 1.

Jaguars: Urban Meyer and Trevor Lawrence started their NFL careers with a 21-37 loss to the Texans. The first overall pick in this year’s draft had an up and down game (332 yds, 3 TDs, 3INTs).

He will face a sterner test in week 2 against the highly-rated Denver defense. The Jaguars’ defense needs to improve against the run to win this game as they gave up 160 yds and 2 TDs last week against a rushing group similar to Denver’s.

The Broncos are heading in as heavy favorites in Week 2 against the Jags. As long as Teddy repeats last week’s heroics, this could be a one-sided game in Jacksonville with the visitors likely to pummel the Jaguars.

I’m taking the -275 on offer.

San Francisco 49ers (-190) @ Philadelphia Eagles (+160)

49ers: The 49ers survived a late comeback from the Lions in week 1 getting off to a winning start after a disappointing 2020 season.

Jimmy Garoppolo had an excellent game (314 yds, 1TD, 0 INT), he looked back to his best and so did the rest of the offense. Elijah Mitchel had a big day rushing (104 yds, 1TD, 5.5 avg) after Raheem Mostert got injured early on and will miss their week 2 game.

Deebo Samual had the most impressive day (9 rec, 189 yds, 1 TD). However, the defense struggled in the second half of the game.

Even though they were able to pressure Jared Goff he still was able to throw for 338 yds. If the 49ers are to win this game the secondary needs to step up and stop Jalen Hurts.

Eagles: The Eagles had a big day out with a 32-6 win over the Falcons. The defense play exceptionally and didn’t allow a single point in the second half.

They will need to continue to play like this if they want to have any chance of stopping Jimmy G and the explosive 49ers offense. The offense for the Eagles had an equally good day out.

Jalen Hurts had many doubts going into this season, however, that didn’t stop him from putting up outstanding numbers (264 yds, 3 TDs, 0 INT, 62 yds rushing).

He also had instant chemistry with DeVonta Smith from their days at Alabama. Jalen Reagor and Dallas Goedert also had good days both catching a TD pass, not to mention that Miles Sanders rushed for 74 yds.

This offense will take a lot of confidence into Sunday’s match and could exploit the 49ers struggling defense.

The 49ers are favorites in this match-up in what could be a very high-scoring game.

This game is too close to call for me but I am taking the Eagles.

Los Angeles Rams (-180) @ Indianapolis Colts (+155)

Rams: The Rams started the season with a dominant win against the Bears. Matthew Stafford started his Rams career with an exceptional 77 completion percentage (321 yds, 3 TDs, 0 INT) which was against a tough defensive front 7 for Chicago.

This was helped by the deep group of quality receivers that the Rams have, with Cooper Kupp being Stafford’ favorite target (10 TGTS, 7 rec, 108 yds, 1 TD). Even with Cam Akers out for a long time, the run game was also productive for the Rams with Darrell Henderson rushing for 70 yds.

They might need to rely on the run game in week 2 with the Colts having an excellent secondary. The defense also played well getting an interception and 3 sacks against an average Chicago offense. The defense is going to have to stop Jonathon Taylor out of the backfield on rushing and passing attempts.

Colts: Carson Wentz started his first game for the Colts on Sunday and lost against the Seahawks. He play well (251 yds, 2 TDs, 0 INT) but wasn’t lights out.

If the Colts are going to win their week 2 matchup against the Rams the Wentz needs to play better against possibly one of the best defenses in the NFL.

The defense also struggled against Seattle, giving up 140 yds rushing and 254 yds passing, they also didn’t make an interception in week one. This will all have to improve to stop a dangerous and well-balanced Rams offense.

The Rams are favorites heading into Sunday’s match. Both teams have good defenses so we could see a relatively low-scoring game.

I am betting on the Rams for this match-up.

Las Vegas Raiders (+215) @ Pittsburgh Steelers (-265)

Raiders: The Raiders had an overtime win over the Ravens in a thrilling game. Derek Carr had a big night (435 yds, 2 TDs, 1 INT) showing his high ceiling as a QB. He completed 34 of his passes but it did take him 56 attempts to do so.

Waller was Carr’s favorite target catching 10/19 for 105 yards, he is growing into one of the best tight ends in football. However, the Raiders couldn’t get much going on the rushing side of the offense which could be a problem in the week 2 match-up.

Their defense played ok and was unable to stop Lamar Jackson from rushing for 80 yards. The defense should be more comfortable against the steelers as there is no running threat from their QB.

Steelers: The Steelers pulled off a big upset win against a Super Bowl contender in the Buffalo Bills. They managed to keep MVP candidate Josh Allen quiet in the red zone forcing the Bills to kick 3 field goals.

They also managed to sack him 3 times. Ben Roethlisberger (188 yds, 1 TD, 0 INT) had a moderate game, only completing about half of his passing attempts, but he was able to distribute the ball to his receivers very well.

It was a real team win, everybody contributed and they did what they had to do to grind out a win even when the offense could get going for much of the afternoon.

It is going to be an intriguing matchup between the Raider’s offense and the Steelers’ defense. The Steelers are heavy favorites to win this game, but if Big Ben doesn’t turn up again then it could make for a close match.

I am betting on the Raiders to win this one.

Cincinnati Bengals (+125) @ Chicago Bears (-145)

Bengals: The Bengals produced an upset win over the Vikings in week 1 with Joe Burrow and Joe Mixon both returning from injury.

Joe Burrow seemed to pick up where he left off last season (261 yds, 2 TDs, 0 INT), he was very accurate and composed in the pocket which helped him to complete 74% of his passes.

The chemistry was clear to see with rookie Ja’Marr Chase who had 101 receiving yards. This is very encouraging for Bengals fans after Chase had a rocky preseason with several drops.

The Bengals’ offensive line did however give up 4 sacks which will concern Zac Taylor after the Bengals spent a lot of money trying to upgrade their O-line.

The defense looked solid against the run but that meant they were exposed in the secondary which is where the Vikings were able to exploit. This could prove to be an interesting matchup against a run-heavy Bears team.

Bears: The Bears took a heavy defeat to the Rams on Sunday. On defense, the secondary was exposed and the strong front seven never really got going.

However, the front seven should be able to make more plays against a weak Bengals line which should help stop Joe Burrow and the Bengals offense. The Bears offense didn’t play to help against the Rams either, Andy Dalton (206 yds, 0 TD, 1 INT) struggled to distribute the ball and was sacked 3 times.

They relied heavily on their run game with David Montgomery rushing for 108 yds. If Andy Dalton can’t get going again on Sunday I wouldn’t be surprised if Justin Fields replaces him again.

The Bears are favorites in this match but if they can’t get the offense working then the Bengals have to take their chances to win.

I am taking the Bears to win this game at home.

Buffalo Bills (-190) @ Miami Dolphins (+160)

Bills: The Bills are coming off a shock defeat at home to the Steelers, where they could never string together a good drive in the second half. Josh Allen wasn’t consistent enough against a good Steelers secondary.

In Week 2 he will face one of the most daunting CB pairings in the league, in Byron Jones and Xavien Howard. However, if the Bills offense from 2020 shows up on Sunday then it will turn into an intriguing matchup against a top 5 defense from 2020.

The Bills defense played well in the first half; not letting the Steelers score a single point, but in the fourth quarter gave up 17 points.

They should find this week more easygoing with an offense that has a lot of explosive receivers but a shaky offensive line and a QB who still hasn’t silenced his doubters.

Dolphins: The Miami Dolphins pulled off a bit of an upset on Sunday by going to New England and winning by one point. The defense had a superb day; stopping the Pats in the red zone four out five times, and also getting a game-winning fumble recovery.

The secondary of this defense looks strong once again with Xavien Howard and Byron Jones only allowing a total of 47 yards.

The pass rush looked solid but the run defense looked a little shaky, giving up 125 yards after losing their NT Raekwon Davis on the first drive of the game he has now been placed on IR.

The Bills who aren’t renowned for their ground game need to test out Miami’s front seven if they want to prevail over this defense. Tua Tagovailoa (202 yds, 1 TD, 1 INT) had an up and down game.

He looked quality on the two touchdown drives but otherwise, he and the offense got bogged down by a good Pats defense.

However, Jalen Waddle (4 rec, 61 yds, 1 TD) looked explosive and got good separation. The Miami offense should improve this weekend as they get Will Fuller back from his suspension.

Miami will need to use the speed of their receivers to open up the Bills’ defense if they want to have any chance of winning this game.

This is going to be a close one to call. The Bills are favorites but I am going to take Miami with a narrow victory at home and its defense shutting down Josh Allen.

Add the Fins to my parlay at +160.

Houston Texans (+410) @ Cleveland Browns (-575)

Texans: The Texans got off to winning ways on Sunday against the Jags. Tyrod Taylor (291 yds, 40 rushing yds, 2 TDs, 0 INT) started his Texans career with a convincing performance, he was able to get out of the pocket and give his receivers time to get open.

They ran the ball well with 170 yards rushing. However, they are coming up against a more accomplished defense in Week 2 which will make it hard for this offense to put up those numbers again.

The defense looked capable but still gave up 332 yards and 3 TDs to a rookie QB, which will worry the coaches. They will face a much tougher test with an explosive all-around Browns offense.

Browns: The Browns gave up a double-digit lead over Kansas to narrowly lose the game. But, Browns fans should be excited with what this quality offense can do this season.

Baker Mayfield threw for 321 yards and completed 75% of his passes; he has continued his excellent form from last season. Baker can do this due to his strength and depth in offensive weapons.

Nick Chubb was the standout, rushing for 83 yards and 2 TDs. They should continue to have joy in this department against an average Texans defense. The Browns defense will be looking to bounce back after an average display against Kansas.

They allowed Mahomes to throw for 337 yards and relinquished 4 TDs. They were solid against the run, only allowing 73 yards but looked threatened by the deep ball.

The Browns are expected to bounce back from their close loss last week, and put in a similar performance this week against the Texans.

The Browns are heavy favorites to win this one and I am expecting a big win for Cleveland; being able to prevail over the Texans on both sides of the ball.

However, I don’t like these odds so I won’t be betting on this match.

New Orleans Saints (-180) @ Carolina Panthers (+155)

Saints: The Saints dismantled Green Bay in their first game. Jameis Winston threw 5 TD passes to an injury-hit receiving corps.

He wasn’t afraid to throw a deep ball as well with Deonte Harris catching two passes for 72 yards. They also developed momentum in the run game with 171 yards rushing. They hope to have some receivers back for the divisional game on Sunday. The Saints defense also looked quality limiting Arron Rodgers to just 133 yards and Jordan Love to 68 yards.

They also had 2 sacks, 2 interceptions, and several QB hits. This helped pave the way to the defense only relinquishing 3 points in the entire game.

The Saints will be brimming with confidence going into this Sunday’s match and will be looking to continue this good form.

Panthers: Carolina also started their season off with a win at home to the Jets. Sam Darnold (279 yds, 1 TD, 0 INT) had a solid first game; he wasn’t afraid to throw a deep ball and the speed of his receivers meant the Panthers were able to stretch the field.

The Panthers also had a solid day rushing with Christian McCaffrey putting up 98 yards. The secondary of the defense looks a bit shaky, giving up 258 yards to a rookie QB.

The matchup in Week 2 becomes exponentially stiffer with the Saints coming off an exceptional first game. The defense will need to step up and try to stop the Saints running game.

The oddsmakers have the Saints as slight favorites but I am predicting a big win for the Saints with Jameis looking to add to his 5 TD passes.

I like the odds on the saints so they will be one of my parlay teams.

Minnesota Vikings (+160) @ Arizona Cardinals (-190)

Vikings: The Vikings had a shock defeat to the Bengals in Week 1. However, there were lots of encouraging signs for Minnesota. Kirk Cousins (351 yds, 2 TDs, 0 INT) put up some impressive stats, and a third receiver stepped up for a change.

Second-year player K.J. Osborn had 76 receiving yards. However, the Vikings weren’t able to run the ball with conviction; Dalvin Cook going for 61 yards. They might struggle to run the ball again this week with Arizona boasting a quality run defense.

The Vikings’ defense didn’t have the greatest of days either, giving up 261 passing yards and 149 rushing yards. But, they were able to pressure the QB well with 5 sacks on Joe Burrow.

They are going to have a challenge stopping dual-threat QB Kyler Murray and his favorite target, DeAndre Hopkins.

Cardinals: Arizona is coming off an elite performance against a playoff contender in the Titans. They were able to put together a fantastic team performance on both offense and defense.

The offense put up 136 rushing yards and 289 passing yards with Murray throwing an impressive 4 TDs. Hopkins was as usual Murray’s favorite target, catching 2 TDs.

The defense also had a stellar game limiting Derrick Henry to just 58 rushing yards and Ryan Tannehill to 212 passing yards.

Chandler Jones was one of the players of the week with 5 solo sacks. If Arizona continues this good form into the Week 2 game then the Vikings don’t stand much of a chance.

The Cardinals are favorites going into this matchup and I agree with the oddsmakers. I expect to see another big game from Kyler Murray on the ground and through the air.

I am going with a safe bet and I am adding the Cardinals to my parlay.

Atlanta Falcons (+550) @ Tampa Bay Buccaneers (-800)

Falcons: The Falcons looked every bit as disheveled as they were expected to be in a season-opening 32-6 loss to the Eagles under new head coach Arthur Smith. Matt Ryan (164 yds, 0 TDs, 0 INT) looked like a different QB without star wide-out Julio Jones.

He couldn’t get to grips with Smith’s brand new offense and it didn’t help that Calvin Ridley and rookie Kyle Pitts were unable to get open a lot of the time.

The Falcons defense struggled against both the run and the pass, giving up big numbers for both. The Falcons now face a much tougher test against the reigning champions.

Buccaneers: Tom Brady produced one of his classic performances to help the Buccaneers over the line against the Cowboys. He threw for 379 yards, 4 TDs, and had a game-winning drive.

All of the Buccaneers receiving corps stepped up with both Antonio Brown and Chris Godwin going for over 100 yards. The Bucs had to rely on their pass offense due to their inability to run the ball; probably their only weakness on the whole team.

Although, the running backs should have an easier time against a poor Falcons run defense. The Bucs defense was excellent against the run, only giving up 60 yards but were slightly blown away by Prescott and the Cowboys receivers, giving up over 400 yards.

They will need to keep a lid on the Falcons danger men, Kyle Pitts and Calvin Ridley.

Tampa Bay is a massive favorite to win this one. I am taking the Bucs with a blow-out win at home.

But, these odds are far too short so I won’t be betting on the game.

Tennessee Titans (+200) @ Seattle Seahawks (-250)

Titans: The Titans are coming off an embarrassing loss to the Arizona Cardinals. The Titans’ offense never strung convincing plays together. The offensive line gave up 6 sacks and plenty more QB pressures.

The run game surprisingly was non-existent and Ryan Tannehill’s (212 yds, 1 TD, 1 INT) numbers weren’t too impressive either. Tennessee needs to get back to its 2020 ways; an accurate Ryan Tannehill and a bulldozing Derrick Henry.

The defense wasn’t much better, only being able to sack Kyler Murray twice and they weren’t able to control the Cardinals running plays.

They will be up against a confident Seattle offense, meaning the Titans’ offense needs to have long plays and keep Russell Wilson off the field for as long as possible.

Seahawks: The Seahawks had a convincing win over the Colts in Week 1. A very accurate Russell Wilson threw an impressive 4 TDs and looked very comfortable throwing to his versatile group of receivers.

Tyler Lockett averaged 25 yards per catch on Sunday with the rest of the group also making big contributions. Seattle’s defense contained Carson Wentz and the Colts passing game to 251 yards.

They also sacked Wentz 3 times and should have more joy rushing the passer against a weak Titans offensive line.

Seattle is the overwhelming favorite for this matchup and I agree with the oddsmakers that Seattle will win at home.

However, these aren’t the best odds and I only have a limited number of bets on my parlay so I won’t be betting on this game.

Dallas Cowboys (+165) @ Los Angeles Chargers (-195)

Cowboys: A valiant display from the Cowboys couldn’t see them over the line last Thursday against the Bucs. Dak Prescott (403 yds, 3 TDs, 1 INT) looked to be back to his best since suffering a horrific ankle injury last season.

The Cowboys had to rely on Dak to throw the ball as they couldn’t get any momentum rushing the ball against a good run defense. That could change with the Chargers having a less well-equipped run defense than the Bucs.

The Cowboys’ top offensive weapons were outstanding with both Amari Cooper and CeeDee Lamb going for over 100 yards. Expect those two to be heavily involved in Sunday’s matchup.

The Cowboys’ defense limited Leonard Fournette to just 32 yards but they did give up 379 yards on pass plays. I am sure Justin Herbert will target the Cowboys’ secondary when he has the time in the pocket.

Chargers: The LA Chargers started the season with a win against a tough Washington team. Justin Herbert (337 yds, 1 TD, 1 INT), Keenan Allen (100 yds), and Mike Williams (82 yds, 1 TD) all thrived in the first game of the season against an intriguing Washington defense.

They should all continue their excellent start to the season against an average Cowboys secondary. The Chargers’ defense played well on Sunday against the pass but they gave up 126 yards rushing and could struggle against Ezekiel Elliott who had a quiet first game.

The odds are in the Chargers’ favor but I am taking the Cowboys with a shock road victory, with Dak continuing his gun-slinger approach.

I am betting for the underdog and adding Dallas to my parlay.

Kansas City Chiefs (-195) @ Baltimore Ravens (+165)

Chiefs: Kansas avoided an upset to squeak past the Browns. Patrick Mahomes (337 yds, 3 TDs, 0 INT) was able to move the ball downfield and connected on some impressive deep throws. Tyrek Hill (197 yds, 1 TD) was able to get open then make defenders miss.

The Chiefs’ defense appeared to be sleeping during the first half, letting the Browns score 22 points. However, they changed dramatically in the second half, only giving up an exceptional 7 points.

Andy Reid will be hoping the second-half defense turns up against the Ravens who have the best dual-threat QB in the league.

Ravens: Baltimore will be disappointed with their overtime loss to the Raiders. Lamar Jackson (235 yds, 86 yds rushing, 1 TD, 0 INT) and the rest of the offense played with intensity and purpose.

The running ability of Jackson meant they totaled 189 yds rushing and we should expect more of that against the Chiefs. The defense couldn’t handle the passing ability of Carr, giving up a total of 435 yards and 2 TDs.

They found it impossible to cover TE Darren Waller who went for over 100 yards, and they could find it tricky to contain Pro Bowl TE Travis Kelce this weekend.

If the Ravens are going to win this match they are going to have to stop Mahomes, Kelce, and Hill from getting into their groove.

Kansas City is the favorite in this match and I am going to agree with the oddsmakers.

I think that the defense will bounce back and stop the Ravens’ unusual offense, the odds are ok but I am adding Kansas to my parlay.

Detroit Lions (+410) @ Green Bay Packers (-575)

Lions: Detroit started their Jared Goff era with a home loss to the 49ers. Goff (338 yds, 3 TDs 1 INT) showed a gutsy performance and attempted an unsuccessful second-half comeback.

Former Packer Jamaal Williams had an outstanding game, with 110 total yards, and so did TE T.J. Hockenson (97 yds, 1 TD). We learned that under new head coach Dan Campbell the Lions are going to be feisty and won’t be an easy opponent to play, especially at home.

We could see some upsets this season caused by the Lions.

Packers: Green Bay is coming off a shocking loss to the Saints. Neither Jordan Love nor Aaron Rodgers could consistently push the offense down the field, which resulted in only 244 yards of total offense for Green Bay.

Their defense didn’t play anywhere near the level we have come to expect from them, giving up 5 touchdowns and not getting a single sack. This was a most un-Green Bay performance that I am sure they will want to prove is an outlier this Sunday against the Lions.

Even though they had a shocking start to the season the Packers are heavy favorites to win this one. I am taking the Packers to take the win on their home soil.

The odds are too short for this match so I am not going to bet on this match.

Check out next week’s NFL betting odds.