MLB Best NRFI Bets Today – April 29, 2025

The last Tuesday of April brings with it a packed 15-game MLB slate rife with NRFI betting opportunities.
Using the incredible BestOdds NRFI Pro, we’ve narrowed down those 15 games down to the three best matchups of the night as far as the NRFI goes. Here’s what we have circled on our betting cards for tonight’s action.

Note: Odds were correct at the time of writing.

Cardinals at Reds NRFI (+100) at Caesars

On the surface, today’s Cards-Reds matchup may not seem like one of the better NRFI betting options, but thanks to BestOdds NRFI Pro, we can go under the hood and take a closer look at the numbers for tonight’s starting pitchers, Miles Mikolas and Brady Singer.

Entering tonight’s game, Mikolas has thrown a scoreless first inning in three of his five starts, while his counterpart, Singer, has done so in four of his five starts this season.

And while we now have a decent sample size from the 2025 MLB season, NRFI Pro also shows that in 2024, both of tonight’s starters excelled at cashing NRFI tickets—each delivered a first-inning shutout in 26 of their 32 starts.

At even money, I’m going to take a shot on these two 2024 NRFI All-Stars to replicate last season’s success.

Miles Mikolas and Brady Singer’s 2025 NRFI Betting Stats Courtesy of NRFI Pro

Odds Comparison for STL-CIN NRFI

Sportsbook	Odds
Caesars	+100 (Best Odds)
FanDuel	-102
bet365	-105
BetMGM	-105
DraftKings	-105

Nationals at Phillies NRFI (-110) at Caesars

For NRFI pick number two, we’re heading to the City of Brotherly Love, where the Nats and Phils kick off a three-game series with a pair of aces taking the mound.

As one might expect when two frontline starters square off, both have been outstanding in the opening frame this season.

Nats starter MacKenzie Gore has delivered a first-inning shutout in five of his six starts, while his counterpart, Zack Wheeler, has yet to surrender a first-inning run in any of his six starts.

If that weren’t enough to get the juices flowing, Gore closed out the 2024 campaign with a scoreless first in 27 of his 32 starts, and Wheeler slightly topped that with 28 scoreless firsts in 32 starts.

Simply put, these two have consistently delivered for NRFI bettors. So who better to trust with a bit of American currency than these two beauties?

Give me the NRFI at the nice price of -110 from our friends at Caesars.

MacKenzie Gore and Zack Wheeler’s 2025 NRFI Betting Stats Courtesy of NRFI Pro

Odds Comparison for WAS-PHI NRFI

Sportsbook	Odds
Caesars	-110 (Best Odds)
bet365	-125
FanDuel	-125
BetMGM	-130
DraftKings	-130

Red Sox at Blue Jays NRFI (-125) at bet365

Our final NRFI pick of the night comes north of the border, as the Red Sox and Blue Jays begin a three-game series at Rogers Centre with Garrett Crochet and Bowden Francis set to face off.

As with our earlier picks, this matchup looks strong on paper when it comes to pitchers delivering those six crucial outs to start the game.

This past offseason, the Red Sox rescued Garrett Crochet from the hellscape that is the White Sox. Since signing a $170 million contract, the former Chicago ace has delivered in a big way. And while Boston surely didn’t pay him solely for his ability to cash NRFI tickets, the flame-throwing lefty has come through in that department as well.

His counterpart tonight, Bowden Francis, has been a pleasant surprise for a Blue Jays rotation full of aging arms. He enters this game with a respectable 3.58 ERA and, more importantly for our purposes, has yet to allow a run in the first inning this season.

Yes, there are dangerous bats at the top of both lineups, but I’m counting on the pitching to have the early edge and deliver us this NRFI.

Garrett Crochet and Bowden Francis’ 2025 NRFI Betting Stats Courtesy of NRFI Pro

Odds Comparison for BOS-TOR NRFI

Sportsbook	Odds
bet365	-125 (Best Odds)
BetMGM	-125 (Best Odds)
Caesars	-125 (Best Odds)
DraftKings	-125 (Best Odds)
FanDuel	-136