2026 NFC West Betting Odds

Entering Week 16, the NFC West looked to be one of the strongest divisions in the NFL withe three teams holding double-digit win totals. At 11-3, the Rams have cinched a…

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BestOddsBetting OddsNFLNFC West Betting
Published:Aug 29, 2025
Updated:Dec 15, 2025
Brent BooherSenior Writer
Eric Kithinji
Fact Checker
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The Rams notched an impressive 41-34 win over the Lions in Week 15 and have a big matchup against the Seahawks in Week 16.

The 49ers close out the season with a tough schedule against the Colts, Bears, and Seahawks. Bringing up the rear of the division is an Arizona Cardinals (3-11) team that began the season 2-0 on the year and has since won just a single game..

Before we dive into the rest of the betting news surrounding the NFC West let’s take a look at the current odds to win the division entering Week 16 action.

USATSI 27309261 - Portrait with football player.

Odds to Win 2025 NFC West Entering Week 7

TeamCurrent Odds to Win NFC WestOdds to Win NFC West Entering Week 8Odds to Win NFC West Entering Week 5Odds to Win NFC West Entering Week 3Preseason Odds to Win NFC West
Los Angeles Rams-170+155+240+175+200
San Francisco 49ers+700+160-105+150+145
Seattle Seahawks+220+250+330+850+550
Arizona CardinalsNR+4500+1600+360+420

If the logjam atop of the division wasn’t enough of an indicator as to how good the NFC West is this season, perhaps the betting odds will shed more light.

Entering Week 16, three teams are still alive with the Rams the current short favorites at -170. However, the Seahawks and Niners still at least have a shot, although San Francisco may need signifcant help to get there.

USATSI 27309623 - Portrait of a football player.

2025 NFC West Win Totals

There is no better way to understand how a division is perceived by the oddsmakers than looking at team win totals as the season goes on.

Here’s how the NFC West shakes out in the win total department following the first six weeks of action.

TeamCurrent Win Totals andBetting OddsWin Totals and Betting Odds Entering Week 8Win Totals and Betting Odds Entering Week 5Win Totals and Betting Odds Entering Week 3Preseason Win Totals andBetting Odds
San Francisco 49ersO/U 11.5 | (-135/+115)O/U 10.5 | (-120/+100)O/U 11.5 | (-110/-110)O/U 10.5 | (-145/+125)O/U 10.5 | (-120/+100)
Los Angeles RamsO/U 13.5 | (+185/-220)O/U 10.5 | (-140/+120)O/U 10.5 | (-115/-105)O/U 10.5 | (-120/+100)O/U 9.5 | (-125/+105)
Seattle SeahawksO/U 12.5 | (-225/+190)O/U 10.5 | (+115/-135)O/U 9.5 | (-160/+135)O/U 8.5 | (+100/-120)O/U 8.5 | (+115/-135)
Arizona CardinalsO/U 3.5 | (-290/+235)O/U 6.5 | (+110/-130)O/U 7.5 | (-135/+115)O/U 9.5 | (-110/-110)O/U 8.5 | (-115/-105)
  • The 49ers began the season as the short favorite to win the division with a projected win total of 10.5. While the team may not be the favorite now, the number of wins has remained steady throughout the season.
  • The Rams have been an unstoppable force for much of the season and seen the win total climb from 9.5 in the preseason to 13.5 now. Over bettors have been handsomely rewarded.
  • The Seahawks have also seen their win total climb significantly throughout the season, now topping out at 12.5. These numbers above show just how competitive this division has been this season.
  • The Cardinals projected win total has nosedived throughout the season. The team lost several close games early, but then some injuries took their toll and the Cards hit a season-low of 3.5.
USATSI 27310264 168395543 - Sports photo with players in action.

2025 NFC West – To Win Super Bowl 60 Odds

Of all the eight divisions in the NFL, only the NFC West features three teams with Super Bowl odds of 30-1 or better. Here’s a look at how the Super Bowl odds measure up for each member of the top division in football as we enter Week 16.

NFC West Teams – Super Bowl LX Odds

TeamCurrent Odds to Win Super Bowl LXOdds to Win Super Bowl LX Entering Week 8Odds to Win Super Bowl LX Entering Week 5Odds to Win Super Bowl LX Entering Week 3Preseason Odds to Win Super Bowl LX
Los Angeles Rams+350+1600+1800+1800+1900
San Francisco 49ers+2000+2200+1900+1900+1800
Seattle Seahawks+700+2700+3300+7000+6000
Arizona CardinalsNE+17500+8000+3500+4000

The Rams and Seahawks are the betting favorites to win the championship. Their odds have seen massive improvement throughout the season.

The odds fo the 49ers to be in the big game have remained pretty consistent, but have tickd up just a bit from +1800 in the preseason to +2000 now.

Meanwhile the Cardinals’ free fall is even more apparent in the Super Bowl futures market as they moved from 35-1 after beginning the year 2-0 to 175-1 entering Week 7. Any hopes for a Cardinals Super Bowl appearance are now gone.

USATSI 27313703 - Sports Photo with NFL players.

2025 NFC West – Player MVP Odds

It’s undeniable now that the NFL MVP award is essentially just a coronation of what quarterback had the best season from the best team.

Here’s how the MVP odds shake out for the quarterbacks from the NFC West.

PlayerCurrent Odds to Win NFL MVPOdds to Win NFL MVP Entering Week 8Odds to Win NFL MVP Entering Week 5Odds to Win NFL MVP Entering Week 3Preseason Odds to Win NFL MVP
Matthew Stafford (Rams)-250+1600+1400+2500+4000
Sam Darnold (Seahawks)+10000+4000+6000+10000+10000
Brock Purdy (49ers)NR+25000+20000+6000+2800
Kyler Murray (Cardinals)NR+50000+20000+5000+5000

Entering Week 16, only two signal callers from the NFL’s top division figure to be in the MVP race at the moment: Matthew Stafford and Sam Darnold. 

Matthew Stafford looks to have a significant edge to win the award, but Darnold at least still has a shot. With several others QBs in the mix, Darnold’s chances, however, are pretty long.

Step-By-Step To Bet On Divisional Winners

1. Go to your favorite sportsbook and log in.2. Look for the NFL tab.3. Click on the Division’s tab from the drop-down menu.4. Choose the odds and team you will bet on.5. Place your bet from the bet slip window—usually—on the right side of the screen.

Betting Odds For NFC Divisions

2026 NFC South Division Odds

2026 NFC North Division Odds

2026 NFC East Division Odds

About the Author: Brent Booher

Die-hard sports fan and overall lover of everything sports betting. Best bet ever placed was a $20 wager on Manchester United to win by the exact score of 3-1 in the 2019 Champions League at 80:1.

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