2025 NFC West Betting Odds

Entering Week 7, only one division in the NFL could boast that they have three teams with four wins or more across their first six games.

That division is none other than the NFC West, or as it may be known throughout the rest of the season, the NFC Best.

As we enter the second to last NFL weekend in October, the NFC West features a three-way tie for first with the Niners, Seahawks, and Rams all tied in the standings at 4-2. Due to the Niners being 3-0 in the division, they would be your division champs if the season ended today, fortunately for the teams in the West not named the Niners, however, the season still has 12 more weeks to reach its conclusion.

Entering Week 7, Mike Shanahan will once again lean on Mac Jones to pilot his offense as Brock Purdy continues to work his way back from a turf toe injury that’s sidelined him for all but two games this season. While the Niners are 4-2, they have dropped two of their last three games and just lost their heart and soul on defense, Fred Warner, to a season-ending ankle injury. At some point one has to figure all of these injuries will catch up to the 49ers, but for the time being they remain atop the division.

The team quickly breathing down the 49ers neck, however, is a team we’ve been warning you about for the last month and change. The Seahawks bounced back against the Jaguars in Week 6 with a dominant performance that saw Sam Darnold and Jaxon Smith-Njigba continue to explode in Klint Kubiak’s scheme. Seattle has won four of their last five games since dropping their season opener against the 49ers, with their lone loss coming in a thrilling 38-35 game against Baker Mayfield and the 5-1 Bucs, a game that Seattle very much could have won.

Sam Darnold has managed to not only replicate his strong play under Kevin O’Connell last season, but in many ways he has exceeded that play from a season ago in his new digs in Seattle. If he continues to play at the rate he is currently, the Seahawks are not only a threat to win the NFC West, but the NFC as a whole.

The current third-place team in the division is another team that figures to be in the mix for the rest of the season as the Los Angeles Rams enter Week 7 with a 4-2 record of their own as Matt Stafford and Puka Nacua continue to torment defenses each week, however, when the Rams face the Jags in London to kick off the Sunday slate in Week 7, Puka Nacua will be on the sidelines nursing a foot injury that knocked him out of action in the Rams Week 6 win over Baltimore.

Nonetheless, Puka is expected back after the Rams Week 8 bye and like the Seahawks, they will remain a strong contender in both the NFC West and NFC in general.

Bringing up the rear of the division is an Arizona Cardinals team that began the season 2-0 on the year and has since lost four straight games while Kyler Murray could potentially miss another start as Jonathan Gannon’s group slowly seems to be coming apart at the seams.

Before we dive into the rest of the betting news surrounding the NFC West let’s take a look at the current odds to win the division entering Week 7’s action.

Odds to Win 2025 NFC West Entering Week 7

Team	Current Odds to Win NFC West	Odds to Win NFC West Entering Week 5	Odds to Win NFC West Entering Week 3	Preseason Odds to Win NFC West
Los Angeles Rams	+155	+240	+175	+200
San Francisco 49ers	+160	-105	+150	+145
Seattle Seahawks	+250	+330	+850	+550
Arizona Cardinals	+4500	+1600	+360	+420

If the logjam atop of the division wasn’t enough of an indicator as to how good the NFC West is this season, perhaps the betting odds will shed more light.

Entering Week 7, three teams are in a virtual dead heat to win the division, with the Rams the current short favorites at +155, however, the Niners are right there with them at +160 and the Seahawks have moved to their shortest odds to win the West this season at +255.

Arizona, understandably so, has cratered to 45-1 to win the division after being offered as low as +360 after their 2-0 start. If you take a peak at their next four games (vs. Packers, at Cowboys, at Seahawks, vs. 49ers) you will see this season can get ugly in a hurry for the Cardinals with Arizona staring at a possible 2-8 record after 10 games.

2025 NFC West Win Totals

There is no better way to understand how a division is perceived by the oddsmakers than looking at team win totals as the season goes on.

Here’s how the NFC West shakes out in the win total department following the first six weeks of action.

Team	Current Win Totals and Betting Odds	Win Totals and Betting Odds Entering Week 5	Win Totals and Betting Odds Entering Week 3	Preseason Win Totals and Betting Odds
San Francisco 49ers	O/U 10.5 | (-120/+100)	O/U 11.5 | (-110/-110)	O/U 10.5 | (-145/+125)	O/U 10.5 | (-120/+100)
Los Angeles Rams	O/U 10.5 | (-140/+120)	O/U 10.5 | (-115/-105)	O/U 10.5 | (-120/+100)	O/U 9.5 | (-125/+105)
Seattle Seahawks	O/U 10.5 | (+115/-135)	O/U 9.5 | (-160/+135)	O/U 8.5 | (+100/-120)	O/U 8.5 | (+115/-135)
Arizona Cardinals	O/U 6.5 | (+110/-130)	O/U 7.5 | (-135/+115)	O/U 9.5 | (-110/-110)	O/U 8.5 | (-115/-105)

• The 49ers began the season as the short favorite to win the division with a projected win total of 10.5 and after their first six games of the season they remain favored to win 10.5 games this season. Entering Week 5, this number ballooned up to 11.5, but after losses in two of their three games and another devastating injury to a key member of their defense, one has to wonder how long Kyle Shanahan can keep everything together.
  
  
• Thanks to their 4-2 start, the Rams projected win total has been bumped from 9.5 to 10.5, with the juice being heavily on the over. It should be noted that while Sean McVay has been incredibly successful in his nine seasons as Rams head coach, he has won 11+ games in a season only three times. Perhaps the under 10.5 at +120 is worth a longer look?
  
  
• The Seahawks went from a projected win total of 8.5 games with juice on the under to a projected win total of 10.5 games after their decisive win over a good Jaguars team that handed the 49ers a home loss and then followed that up with a win over a Chiefs team that could arguably be the team to beat in the AFC at the moment. We’ve said it all season long, this Seattle team is flying under the radar. However, oddsmakers may finally be catching up to their potential, will the betting public follow suit?
  
  
• The Cardinals projected win total has slid from 9.5 after their 2-0 start to the season to 6.5 after their four-game losing streak. A couple weeks ago we would have found it crazy to think Arizona would finish 6-11 or worse, however, looking at their schedule, Arizona is in grave danger of having a really bad season. Of their 11 remaining games, only three opponents currently have a sub-.500 record. Basically, the under 6.5 looks really good right now. 
  

2025 NFC West – To Win Super Bowl 60 Odds

Of all the eight divisions in the NFL, only the NFC West features three teams with Super Bowl odds of 30-1 or better.

Could the division send three teams to the playoffs like the NFC North did in 2024? It sure looks like they’re on their way.

Here’s a look at how the Super Bowl odds measure up for each member of the top division in football as we enter Week 7.

NFC West Teams – Super Bowl LX Odds

Team	Current Odds to Win Super Bowl LX	Odds to Win Super Bowl LX Entering Week 5	Odds to Win Super Bowl LX Entering Week 3	Preseason Odds to Win Super Bowl LX
Los Angeles Rams	+1600	+1800	+1800	+1900
San Francisco 49ers	+2200	+1900	+1900	+1800
Seattle Seahawks	+2700	+3300	+7000	+6000
Arizona Cardinals	+17500	+8000	+3500	+4000

The Rams and 49ers Super Bowl odds have mostly remained stagnant throughout the season, with the Rams modestly improving from 18-1 to 16-1 over the last two weeks and the Niners slightly dropping from 19-1 to 22-1. 

The team that has been surging up the Super Bowl futures board over the last month is that of Sam Darnold’s Seattle Seahawks, who enter Week 7 with 27-1 odds to win the Super Bowl, their lowest of the season to date. After the Seahawks beat the Steelers to climb to 1-1 on the season you could have grabbed them at 70-1 to win the Super Bowl. You won’t find that price now.

Meanwhile the Cardinals free fall is even more apparent in the Super Bowl futures market as they moved from 35-1 after beginning the year 2-0 to 175-1 entering Week 7. There is no real reason to think this is about to change for the better anytime soon.

2025 NFC West – Player MVP Odds

It’s undeniable now that the NFL MVP award is essentially just a coronation of what quarterback had the best season from the best team.

Here’s how the MVP odds shake out for the quarterbacks from the NFC West.

Player	Current Odds to Win NFL MVP	Odds to Win NFL MVP Entering Week 5	Odds to Win NFL MVP Entering Week 3	Preseason Odds to Win NFL MVP
Matthew Stafford (Rams)	+1600	+1400	+2500	+4000
Sam Darnold (Seahawks)	+4000	+6000	+10000	+10000
Brock Purdy (49ers)	+25000	+20000	+6000	+2800
Kyler Murray (Cardinals)	+50000	+20000	+5000	+5000

Entering Week 7, only two signal callers from the NFL’s top division figure to be in the MVP race at the moment: Matthew Stafford and Sam Darnold. 

We still believe Darnold’s odds are too low, as he’s a freakish bounce off a defensive tackle’s head away from having the same MVP push as Baker Mayfield. If he continues to perform at the level he’s been playing at since the Week 1 loss to San Francisco, he’s going to factor into this race more than people want to believe at this point.

Stafford continues to put up the numbers to hang around this race as well, and if he performs at a high level without Nacua in the lineup, that will only strengthen his resume. play taking the wind out of his sails and Kyler Murray having some tough games during a recent losing skid basically ending his hopes.

Step-By-Step To Bet On Divisional Winners

1. Go to your favorite sportsbook and log in.
2. Look for the NFL tab.
3. Click on the Division’s tab from the drop-down menu.
4. Choose the odds and team you will bet on.
5. Place your bet from the bet slip window—usually—on the right side of the screen.

Betting Odds For NFC Divisions

2025 NFC South Division Odds

2025 NFC North Division Odds

2025 NFC East Division Odds