2025 NFC South Betting Odds

Brent Booher

Sadonna Price
The NFC South is often seen as one of the worst divisions in all of the National Football League and the first month of play did not do much to quell those accusations.
The teams not named the Tampa Bay Buccaneers are a combined 3-9 in the division as we enter Week 5 and the Falcons are responsible for two of those three victories.
Like I said, they haven’t done themselves many favors in shedding that whole worst division label thing.
Nonetheless the NFC South will eventually field a playoff team, and that team looks sneakily dangerous. Before we dive into everything NFC South lets take a look at the betting odds to win the division as we enter October.

Odds to Win 2025 NFC South Entering Week 5
Team | Current Odds to Win NFC South | Odds to Win NFC South Entering Week 3 | Preseason Odds to Win NFC South |
Tampa Bay Buccaneers | -240 | -180 | -105 |
Atlanta Falcons | +290 | +200 | +230 |
Carolina Panthers | +1300 | +1700 | +400 |
New Orleans Saints | +2700 | +2200 | +1300 |
The Bucs are coming off of a hard fought 31-25 loss against the Eagles in Week 4, giving Tampa its first taste of defeat this season. Despite the defeat Tampa Bay still is the decisive favorite to win the division at -240, this after opening the year at -105.
The only other team with a respectable record this season from the NFC South is that of the Atlanta Falcons who sit at 2-2 after the first four weeks of the season. Michael Penix Jr. has had an up and down start to his early career, but Bijan Robinson has been spectacular and could keep the Falcons in contention on his own, especially as the Bucs are going through a bit of an injury spell against a tough date against the Seahawks in Week 5.
The Panthers and Saints are two of the worst teams in the NFL and both of them are extreme long shots to get back into this division race.

2025 NFC South Win Totals
As one would probably expect, the NFC South is not expected to light the NFL on fire this season, and so far they certainly have not turned many heads.
If you ever need that confirmation as to what oddsmakers think of the division, look no further than the projected win totals for each of the four teams after the first month of play.
Team | Current Win Totals and Betting Odds | Win Totals and Betting Odds Entering Week 3 | Preseason Win Totals and Betting Odds |
Tampa Bay Buccaneers | O/U 10.5 | (+105/-125) | O/U 10.5 | (-120/+100) | O/U 9.5 | (+100/-120) |
Atlanta Falcons | O/U 8.5 | (+100/-120) | O/U 9.5 | (+110/-130) | O/U 7.5 | (-135/+115) |
Carolina Panthers | O/U 5.5 | (+105/-125) | O/U 5.5 | (+120/-140) | O/U 6.5 | (-130/+110) |
New Orleans Saints | O/U 4.5 | (+115/-135) | O/U 4.5 | (-110/-110) | O/U 5.5 | (+140/-165) |
- The Bucs win total remains unchanged from two weeks ago with the number still set at 10.5, however, you can now get plus-money on the over if that sort of thing appeals to you.
- The Falcons win total number continues to bounce around the .500 mark which is fitting for this Atlanta team that will likely hover around .500 all season long.
- The Panthers appearance in Super Bowl 50 feels like an eternity ago, and Cam Newton still hasn’t jumped on that fumble. Bryce Young has a fun new weapon in Tet McMillan, but Carolina once again looks like it’s in for a bumpy season. Their win total has dropped from 6.5 in the preseason to 5.5 now.
- The Saints win total remains at 4.5 with heavier juice towards the under meaning oddsmakers don’t see this New Orleans team winning more than 4 games.

2025 NFC South – To Win Super Bowl 60 Odds
After the first month of the season, we can essentially eliminate the Panthers and Saints from Super Bowl contention, and while Tampa and Atlanta figure to compete for the division crown, neither of these teams strike me as ones to seriously consider as a Super Bowl contender.
Nonetheless, here’s how their Super Bowl odds stack up entering Week 5.
NFC South Teams – Super Bowl LX Odds
Team | Current Odds to Win Super Bowl LX | Odds to Win Super Bowl LX Entering Week 3 | Preseason Odds to Win Super Bowl LX |
Tampa Bay Buccaneers | +3000 | +2200 | +2700 |
Atlanta Falcons | +8000 | +5000 | +6500 |
Carolina Panthers | +40000 | +40000 | +15000 |
New Orleans Saints | +40000 | +40000 | +40000 |

2025 NFC South – Player MVP Odds
The NFL MVP is essentially just a coronation of who was the best quarterback in the NFL that season, and if you’re looking for great NFL MVP bets, this is not the division for you.
With that being said, here’s a look at how each of the four starters in this division measure up in the race for MVP.
Player | Current Odds to Win NFL MVP | Odds to Win NFL MVP Entering Week 3 | Preseason Odds to Win NFL MVP |
Baker Mayfield (Buccaneers) | +2200 | +2000 | +2500 |
Michael Penix Jr. (Falcons) | +17500 | +7500 | +6000 |
Bryce Young (Panthers) | +40000 | +17500 | +10000 |
Spencer Rattler (Saints) | +50000 | +35000 | NR |
Baker Mayfield is your most realistic option from this division to win the MVP, with respectable 22-1 odds entering Week 5. Baker will need to work the next few weeks without Bucky Irving and Mike Evans, which certainly helps the narrative behind MVP consideration but could hurt the output as he plays without two of his biggest weapons on offense.
Michael Penix, Bryce Young and Spencer Rattler are all extreme long shots with absolutely no chance of being in the mix for MVP.
Step-By-Step To Bet On Divisional Winners
1. Go to your favorite sportsbook and log in.
2. Look for the NFL tab.
3. Click on the Division’s tab from the drop-down menu.
4. Choose the odds and team you will bet on.
5. Place your bet from the bet slip window—usually—on the right side of the screen.
Betting Odds For NFC Divisions

