San Francisco 49ers vs. Jacksonville Jaguars: Betting Odds & Game Analysis | NFL Week 11 Predictions

Ed Winchester
November 15, 2021 8:39 PM

The San Francisco 49ers (3-5) are favored by 6 points against the Jacksonville Jaguars (2-7) on November 21, 2021, starting at 1:00 PM ET. The over/under for this one is set at 46.5 points.

Welcome to the BestOdds betting breakdown where we use data from our industry leading partner, Sportradar, to identify performance trends in order to analyze teams’ chances in the upcoming game.

Today, we are looking at the NFL matchup between the San Francisco 49ers and Jacksonville Jaguars in which the 49ers are currently the pick to cover the spread at sportsbooks based on money wagered, yet the Jaguars have picked up a respectable amount of the total number of tickets wagered.

49ers Vs. Jaguars Spread Betting Action

49ers vs Jaguars Moneyline Action
49ers Jaguars
Bet % 52% 48%
Stake % 69% 31%

San Francisco stats and betting info

Betting trends for San Francisco

  • San Francisco is 2-6-0 against the spread this season.
  • The 49ers are 0-1 against the spread when favored by 6 points or more this season.
  • San Francisco has hit the over in five of its eight games with a set total (62.5%).
Stat Average (Total) Rank
Pass yards 263.5 (2108) 13
Rush yards 113.1 (905) 16
Points scored 23.1 (185) 21
Pass yards against 223.0 (1784) 6
Rush yards against 131.6 (1053) 28
Points allowed 25.3 (202) 24

Key players for San Francisco

  • Jimmy Garoppolo has compiled 1,754 yards (219.3 ypg) on 139-of-213 passing with eight touchdowns compared to five interceptions this season.
  • Elijah Mitchell has 469 rushing yards on 89 carries with three touchdowns.
  • Trey Sermon has piled up 135 yards on 31 attempts, scoring one time.
  • Deebo Samuel’s 882 yards as a receiver pace the team. He’s been targeted 81 times and has collected 49 catches and four touchdowns.
  • George Kittle has caught 25 passes for 328 yards (41.0 yards per game) and one touchdown this year.
  • Brandon Aiyuk has hauled in 19 catches for 230 yards, an average of 28.8 yards per game. He’s scored two times as a receiver this season.

San Francisco injuries

49ers: No Injuries Listed

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Jacksonville stats and betting info

Betting trends for Jacksonville

  • Jacksonville is 4-5-0 against the spread this season.
  • The Jaguars are 3-2 against the spread when an underdog by 6 points or more this season.
  • Jacksonville has gone over in two of nine games with a set total (22.2%).
Stat Average (Total) Rank
Pass yards 224.0 (2016) 27
Rush yards 119.0 (1071) 11
Points scored 16.6 (149) 31
Pass yards against 274.8 (2473) 24
Rush yards against 106.0 (954) 11
Points allowed 25.8 (232) 27

Key players for Jacksonville

  • Trevor Lawrence has 1,983 passing yards, or 220.3 per game, so far this season. He has completed 58% of his passes and has recorded eight touchdowns with nine interceptions. He’s also helped out on the ground with 18.8 rushing yards per game while scoring as a runner two times.
  • James Robinson is his team’s leading rusher with 100 carries for 539 yards, or 59.9 per game. He’s found paydirt six times on the ground, as well. Robinson has also chipped in with 22 catches for 160 yards.
  • Carlos Hyde has been given 56 carries and totaled 211 yards.
  • Marvin Jones Jr.’s 434 receiving yards (48.2 yards per game) are best on his team. He has 38 receptions on 66 targets with three touchdowns.
  • Dan Arnold has collected 399 receiving yards (44.3 yards per game) on 34 receptions.
  • Laviska Shenault Jr.’s 35 catches (on 57 targets) have netted him 358 yards (39.8 ypg).

Jacksonville injuries

Jaguars: No Injuries Listed

Pick for 49ers vs. Jaguars

Betting split data provided by regulated betting sites paired with our in-depth statistical analysis favors the 49ers to cover the spread against the Jaguars.

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