College Football Week 4 Loaded With Major SEC and Big Ten Matchups

The 2026 college football season moves deeper into conference play this weekend with a Week 4 schedule featuring several games that could have significant implications for the College Football Playoff race. No. 1 Texas faces its first road test as the Longhorns travel to No. 14 Tennessee, while No. 2 Georgia hosts Oklahoma. The Big Ten also offers two ranked matchups with Iowa visiting Michigan and Oregon traveling to USC.

Texas Faces Major Test at Tennessee

Longhorns Head to Knoxville

Texas remained No. 1 after improving to 3-0 with a 30-6 victory over UTSA. The Longhorns previously produced one of the season’s biggest wins by rallying past Ohio State 24-23. Saturday brings a much more difficult environment at Neyland Stadium. Texas is currently around a 5.5-point road favorite at FanDuel, with an over/under of 55.5. Quarterback Arch Manning will be one of the main players to watch as Texas attempts to remain unbeaten.

Georgia Taes on Arkansas

Georgia is also undefeated and coming off a 45-17 road victory over Arkansas. The Bulldogs now host an Oklahoma team that has struggled offensively in consecutive weeks but hasn’t allowed more than 17 points in a game this season. Georgia is favored by approximately 14 points.

Biggest College Football Games This Weekend

Ranked Matchups Dominate Saturday

• No. 1 Texas at No. 14 Tennessee: Saturday, noon ET, ABC. Texas -5.5; O/U 55.5. Manning and the Texas offense face their first true road environment of the season against an unbeaten Tennessee team.
• Oklahoma at No. 2 Georgia: Saturday, 3:30 p.m. ET. Georgia -14; O/U 43.5. Oklahoma quarterback John Mateer faces a major test against Georgia’s defense, while the Sooners’ defense may need to keep the score low to give Oklahoma an opportunity late.
• No. 17 Iowa at No. 18 Michigan: Saturday, 3:30 p.m. ET, CBS. Michigan -5.5; O/U 38.5. The low total points toward a defensive matchup. Michigan quarterback Bryce Underwood will try to continue developing after the Wolverines improved to 3-0.
• No. 4 Ole Miss at No. 21 Florida: Saturday, 3:30 p.m. ET. Florida -3; O/U 60.5. Ole Miss moved into the top five following a 32-24 victory over LSU. Quarterback Trinidad Chambliss has emerged as one of the country’s early-season standouts.
• No. 20 Oregon at No. 12 USC: Saturday, 7:30 p.m. ET, NBC. Oregon -2.5; O/U 62.5. This matchup carries one of the weekend’s highest totals and gives Oregon an opportunity to rebuild its résumé after its earlier upset loss to Oklahoma State.
• No. 23 Texas A&M at No. 10 LSU: Saturday, 7:30 p.m. ET. LSU -9.5; O/U 52.5. Both teams are trying to rebound from Week 3 losses, giving the SEC matchup additional importance.

National Championship Betting Outlook

Ohio State Remains the Futures Favorite

Despite losing to Texas earlier this season, Ohio State remains the shortest-priced team in the DraftKings national championship market. Texas and Georgia have moved closer to the Buckeyes, while Ole Miss made one of the largest jumps following its victory over LSU. The top eight national championship futures at DraftKings as of the latest update are:

• Ohio State: +520
• Texas: +620
• Georgia: +650
• Notre Dame: +650
• Miami: +850
• Indiana: +950
• Ole Miss: +1500
• LSU: +1600

Those futures could look considerably different by Saturday night. Texas-Tennessee and Oklahoma-Georgia give two leading contenders major SEC tests, while Ole Miss, LSU, Oregon and USC all have opportunities to improve or damage their early playoff résumés. With ranked games stretching from noon through Saturday night, Week 4 represents one of the deepest college football schedules of the young season.