NFL Week 3 Odds 2026

The NFL can certainly seem like a crazy league as favorites saw some tough sledding in Week 2.

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Published:Sep 23, 2021
Updated:Jan 23, 2026
Sean ChaffinSenior Writer

Only four NFC teams remain unbeaten after only two weeks – and not necessarily most prognosticators’ favorite picks.

Through two weeks, the Seahawks, Vikings, Saints, and Buccaneers are the only teams with unblemished records with top squads like the Cowboys, Eagles, Lions, and 49ers all finding early-season losses.

This type of environment can be challenging for bettors, but there is a bit more stability in the AFC where the Bills, Chiefs, Steelers, and Texans have all jumped out to nice starts at 2-0.

Week 3 brings more spicy matchups including an interesting AFC East battle between the Jets and Patriots on Thursday night, with both teams at 1-1.

Here’s a look at what to expect with this week’s NFL betting lines.

Matchups to Watch

Beyond Thursday night’s showdown, a few more games on this week’s slate offer nice storylines. Are teams like the Saints and Vikings for real?

Both have a chance to prove that this week after some nice wins on Sunday.

Will the Falcons build on Monday night’s last-second win over the Eagles?

The birds have their work cut out for them this week, squaring off against the Super Bowl champion Chiefs.

Here’s a look at some big games to check out this week:

  • Patriots at Jets – The Pats shined in Week 1, but then fell off against the Seahawks on Sunday and the Jets notched a win over the Titans last week. In a competitive AFC East, each of these franchises need a win in this one.
  • Eagles at Saints – The Saints demolished the Cowboys on Sunday and the Eagles are coming off a tough loss at home to Atlanta. 
  • Texans at Vikings – These two unbeaten squads have been solid so far. The Vikings impressed after a Week 2 win over the 49ers and the Texans have picked up where they left off last season.
  • Chargers at Steelers – Pittsburgh always seems to be competitive and have started 2024 at 2-0 despite an offense that has only put up a total of 31 points in the first two games.
  • Chiefs at Falcons – This looks like an interesting contest after the Chiefs survived in Week 2. Bijahn Robinson continues to be a force in Atlanta and this may be a great game.

Week 3 NFL Odds

Ready to make those bets for this week’s action?

Here’s a look at this week’s odds, courtesy of FanDuel.

MatchupBetting LineMoneylineTotal
Patriots at JetsJets -6.5Patriots +250Jets -28037.5
Giants at BrownsBrowns -6.5Giants +240Browns – 29538.5
Bears at ColtsColts -2Bears +116Colts -13042.5
Texans at VikingsTexans -2.5Texans -142Vikings +12045.5
Eagles at SaintsSaints -1.5Eagles +108Saints -12649.5
Chargers at SteelersSteelers -1.5Chargers +106Steelers -12435.5
Broncos at BuccaneersBuccaneers -6.5Broncos +245Buccaneers -30039.5
Packers at TitansTitans -2.5Packers +134Titans -15836.5
Panthers at RaidersRaiders -5.5Panthers +200Raiders -24540.5
Dolphins at SeahawksSeahawks -5.5Dolphins +205Seahawks -25041.5
Lions at CardinalsLions -3Lions -146Cardinals +12452.5
Ravens at CowboysRavens -1.5Ravens -112Cowboys -10449.5
49ers at Rams49ers -7.549ers -360Rams +29043.5
Chiefs at FalconsChiefs -3.5Chiefs -190Falcons +16046.5
Jaguars at BillsBills -2.5Jaguars +220Bills -26045.5
Commanders at BengalsBengals -8.5Commanders +330Bengals -42048.5

Interesting Prop Bets

The Cowboys defense has given up over 400 yards of offense in two of the last three games – against the Saints last week and the Packers to end last season in the playoffs.

The team’s rushing defense has really struggled and now faces the Ravens, who need a win, and bruising running back Derrick Henry has a touchdown in the team’s first two games.

Expect that to continue to cash in on the anytime TD bet at -140 and given the Cowboys’ defensive struggles, that first and second-half bet looks good as well at +500 and +600.

Picks for the People

Making those NFL picks isn’t easy as there seems to be a few teams that rise up unexpectedly each week.

We once again went 3-3 last week after our prop bet selection came up just a bit short.

Hopefully, this week sees some better outcomes and here are a few picks to watch:

  • Giants at Browns – Sometimes you go with the hot hand, and sometimes you simply bet against a loser. The Giants look awful and fading the 6.5 points is a good idea here.
  • Panthers at Raiders – Maxx Crosby is a beast for the Raiders and may feast on Panthers on the Panthers. Quarterback Bryce Young has been benched, but that may not matter. Carolina continues cashing checks for bettors as the Reindeers top the 5.5 here.
  • Eagles at Saints –Philadelphia has a short week after a tough Monday night loss and the Saints have looked good so far. Take the Saints to beat that 1.5 spread in a noon game.
  • Patriots at Jets – The Pats have been game this year and are good on the road. That defense should keep this one close and within the 6.5 points.
  • Dolphins at Seahawks – Look for the Dolphins offense to bounce back and these two to hit the over of 41.5.

If you’re interested in our player props and parlay picks for this week, see our newest articles:

About the Author: Sean Chaffin

Sean Chaffin is a freelance writer and former teacher in Ruidoso, New Mexico. He has covered poker and casino gaming for many years, and is a big football fan. Follow him @PokerTraditions.

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