49ers vs. Seahawks Same Game Parlay | Week 12

The San Francisco 49ers and the Seattle Seahawks meet in an NFC West showdown on Thanksgiving night.

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BestOddsBetting OddsNFLWeek 12 NFL Sgp 49Ers Vs Seahawks
Published:Nov 23, 2023
Updated:Jan 23, 2026
Thomas SnodgrassSenior Writer

If the 6-4 Seahawks can pull off a win against the 7-3 49ers, the NFC West will be all tied up at the top.

It may be a difficult task for Seattle, considering that starting quarterback Geno Smith is currently dealing with a triceps injury and running back Kenneth Walker III is suffering from an oblique issue.

Seahawks’ wide receiver DK Metcalf is also listed as ‘questionable’ with a toe injury and was listed as a non-participant in Tuesday’s practice, so Metcalf is another potential absence to monitor prior to kickoff.

For this Thanksgiving Night divisional rivalry, I’ll be placing a Same Game Parlay on FanDuel.

Brock Purdy – OVER 250.5 Passing Yards AND OVER 1.5 TD Passes

Purdy is averaging 266.2 passing yards per game, and against the Seahawks’ 22nd-ranked passing defense, he has a good shot at hitting the over on his 250.5 yards prop.

In the last four games, Purdy has thrown for a chunk of yards, eclipsing the 300-yard mark twice and averaging 316.5 passing yards per game.

Purdy also has back-to-back games of three touchdown passes, so collecting two on Thursday is certainly within reach.

The 49ers had a three-game losing streak prior to their Week 9 bye, but out of the bye week, they’re 2-0 with a combined score of 61-17.

This is largely due to the ridiculously strong play from Purdy.

This is the same Seahawks’ defense that allowed Andy Dalton of the Carolina Panthers to throw for 361 yards and two touchdowns in Week 3.

Week 3 was a while ago, but lapses in Seattle’s secondary reappear from time to time.

Sam Howell of the Commanders just posted 312 yards and three touchdowns against the Seahawks two weeks ago.

Purdy has a good matchup to record a nice Thanksgiving Night.

Pick: Purdy – OVER 250.5 Passing Yards (-114)

Pick: Purdy – OVER 1.5 TD Passes (-148)

Christian McCaffrey – OVER 75.5 Rushing Yards AND Any Time Touchdown

I believe the game script will eventually call for the 49ers to run out the clock on a big lead, so I would expect McCaffrey to receive plenty of carries in this one.

Similar to last week, San Francisco took a commanding lead against the Tampa Bay Buccaneers and McCaffrey saw 21 carries.

It was the fourth game of the season in which McCaffrey saw 20 or more carries.

Here’s a quick look at how McCaffrey has fared when taking 20 or more carries:

OpponentCarriesMcCaffrey’s Results
Week 1: Pittsburgh22152 Yards, TD
Week 2: Los Angeles (N)20116 Yards, TD
Week 4: Arizona20106 Yards, TD
Week 11: Tampa Bay2178 Yards

In those four games with a heavy workload on the ground, McCaffrey is averaging 113 yards and 1.25 rushing touchdowns.

Seattle allowed 77 rushing yards to Royce Freeman of the Los Angeles Rams last week, so McCaffrey collecting 80 yards on the ground seems like a likely result.

Pick: McCaffrey – OVER 75.5 Rushing Yards (-114)

Pick: McCaffrey – Any Time Touchdown

George Kittle – OVER 48.5 Receiving Yards AND Any Time Touchdown

In the Seahawks’ last five games, they have allowed a total of 34 catches for 339 yards and one touchdown to tight ends.

That’s an average of 6.8 catches and 67.8 yards per game to tight ends in the last five weeks.

Kittle collecting six catches for 60 yards against Seattle on Thursday is a realistic result, and BestOdds EDGE projects the 49ers’ explosive tight end for 56 receiving yards.

Kittle would only need 49 yards to hit the over on his receiving yards prop, which is a number he has reached in six of 10 games this season.

Kittle has been producing big numbers of late, benefitting heavily from Purdy’s recent surge.

In the last four games, Kittle is averaging 6.25 catches and 108 receiving yards, and he has scored touchdowns in each of the last two games.

The Purdy-to-Kittle connection is on fire right now, and I’m going to stick with it until it cools off.

Pick: Kittle – OVER 48.5 Receiving Yards (-114)

Pick: Kittle – Any Time Touchdown (+170)

Jaxon Smith-Njigba – OVER 36.5 Receiving Yards

Chances are that Seattle will be playing from behind for the majority of this game.

That’s just what I’m assuming from a game script I’ve played out in my own head.

If that scenario is as likely as I believe it to be, then there should be plenty of pass attempts coming from the arm of the Seahawks’ quarterback; whoever it may be.

If DK Metcalf is limited, or in street clothes on the sideline, I like Jaxon Smith-Njigba to make an impact for Seattle’s offense.

This chart, courtesy of BetsOdds EDGE, shows how Smith-Njigba has been performing against his receiving yards props.

Smith-Njigba is typically hitting the over on his props, and in the last five games, he is averaging 51 receiving yards per game.

The rookie receiver should see enough targets, and make enough catches, to go over his 36.5 receiving yards prop.

Pick: Smith-Njigba – OVER 36.5 Receiving Yards (-114)

FanDuel SGP LegsOdds
Brock Purdy – OVER 250.5 Passing Yards-114
Brock Purdy – OVER 1.5 TD Passes-148
Christian McCaffrey – OVER 75.5 Rushing Yards-114
Christian McCaffrey – Any Time Touchdown-210
George Kittle – OVER 48.5 Receiving Yards-118
George Kittle – Any Time Touchdown+170
Jaxson Smith-Njigba – OVER 36.5 Receiving Yards-114
49ers vs. Seahawks SGP Odds+2678

A $10 wager on this Same Game Parlay would win $267.89!

Betting NFL Same Game Parlays

Same game parlay is just like a regular NFL parlay bet, except all bet selections come from different wagers within one football game.

The benefit of an NFL same game parlay is achieved by combining multiple bets so you can go for bigger wins as the odds increase.

The more bet selections you add, the more difficult it is to win, but the odds also greatly increase so is the potential winning amount.

BestOdds is the ultimate website for NFL bettors new and old. We offer educational content on the latest news and the best betting site options to bet on NFL football. Support us by signing up for one of the recommended sportsbooks and make sure to follow us on social!

About the Author: Thomas Snodgrass

A fan of both the Cleveland Browns and Pittsburgh Steelers, which is rare! Thomas provides sports betting content with the intent to educate and entertain. A lover of sports statistics and the stories those stats tell. A Pittsburgh Pirates follower that has become calloused by the Pirates\' ineptitude. His best bet was a 5-Leg College Football underdog parlay with odds of +64000. He only wagered $0.50 on it.

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